Biologics

    WHP provides integrated design, construction, validation and maintenance of hygienic, sterile processing environments and manufacturing facilities for the biotechnology industry.

    From small to large scale – R&D to production scale processing plant, cleanroom and laboratory construction, WHP has experience in the design and construction of multipurpose contract facilities and dedicated product manufacturing facilities.

    WHP’s competency in the biotechnology industry spans more than three decades, covering:

    • Bacterial
    • Fungal
    • Mammalian and insect cell lines
    • Viral
    • Algal

    The nature of these projects has ranged from lab-scale development, pilot plants to full commercial scale production. WHP has expertise in:

    • Cell factories, cell culture and tissue culture
    • Fermentation – conventional stirred tank, airlift, and custom designs, using disposable or re-usable materials
    • Feedstock and media preparation
    • Primary separation
    • Down stream processing – centrifugation, filtration, chromatography, ultra filtration
    • Media and buffer handling and preparation
    • Contained drain systems
    • Effluent treatment and kill systems
    • Process architecture
    • Facility segregation, containment and flows including HVAC
    • Critical utilities and high purity services (purified water WFI, pure steam, gases, CIP etc.)
    • In-process and product storage

    WHP designs and constructs with best practice for Current Good Manufacturing Practice (cGMP) where validation and quality assurance are essential. WHP also works within UK Medicines and Healthcare Products Regulatory Agency (MHRA) and USA Food and Drug Administration (FDA) regulatory requirements and guidelines.

    Integrated design, construction, validation and maintenance of hygienic, sterile processing environments and manufacturing facilities.

    projects